| Date | Location | Result | |
| 03/02/10 | Radford, Va. -- Dedmon Center | Radford 64, Charleston Southern 61 | Box score |
| 02-27-10 | CSU Field House (Charleston, S.C.) | Liberty 74, Charleston Southern 61 | Box score |
| 02-25-10 | CSU Field House, Charleston, S.C. | Charleston Southern 95, VMI 85 | Box score |
| 02-20-10 | Conway, S.C. (Kimbel Arena) | Coastal Carolina 47, Charleston Southern 37 | Box score |
| 02-16-10 | CSU Field House, Charleston, S.C. | Charleston Southern 94, North Greenville 65 | Box score |
| 2-13-10 | Millis Center, High Point, N.C. | High Point 73, Charleston Southern 68 | Box score |
| 02/11/10 | Radford, Va. -- Dedmon Center | Radford 61, Charleston Southern 58 | Box score |
| 02-06-10 | CSU Field House, Charleston, S.C. | Gardner-Webb 82, Charleston Southern 73 | Box score |
| 02-04-10 | CSU Field House, Charleston, S.C. | Charleston Southern 62, UNC Asheville 54 | Box score |
| 01/30/10 | Templeton Cener (Clinton, S.C.) | Presbyterian College 58, Charleston Southern 51 | Box score |
| 01-28-10 | Winthrop Coliseum--Rock Hill, SC | Winthrop 55, Charleston Southern 53 | Box score |
| 01-23-10 | CSU Field House, Charleston, S.C. | Coastal Carolina 64, Charleston Southern 56 | Box score |
| 01-16-10 | CSU Field House, Charleston, S.C. | Charleston Southern 70, Radford 55 | Box score |
| 01-14-10 | CSU Field House, Charleston, S.C. | Charleston Southern 73, High Point 69 | Box score |
| 1-09-10 | Asheville, N.C./Justice Center | Charleston Southern 77, UNC Asheville 74 | Box score |
| 01/07/10 | Boiling Springs, NC / Paul Porter Arena | Gardner-Webb 64, Charleston Southern 61 | Box score |
| 01-04-10 | CSU Field House, Charleston, S.C. | Charleston Southern 57, Winthrop 54 | Box score |
| 01-02-10 | CSU Field House, Charleston, S.C. | Charleston Southern 79, Presbyterian College 73 | Box score |
| 12/29/09 | Auburn, Ala. | Auburn 77, Charleston Southern 62 | Box score |
| 12-21-09 | Charleston, S.C. | Charleston Southern 94, Southeastern 66 | Box score |
| 12/19/09 | Cassell Coliseum, Blacksburg, Va. | Virginia Tech 73, Charleston Southern 50 | Box score |
| 12/16/09 | Carolina First Arena | College of Charleston 87, Charleston Southern 74 | Box score |
| 12/5/09 | Lexington, Va. (Cameron Hall) | VMI 103, Charleston Southern 91 | Box score |
| 12-03-09 | Lynchburg, Va. - Vines Center | Liberty 69, Charleston Southern 53 | Box score |
| 11-30-09 | Charleston, S.C. | Charleston Southern 103, Toccoa Falls College 53 | Box score |
| 11/28/09 | Clune Arena (USAFA, Colo.) | Air Force 68, Charleston Southern 58 | Box score |
| 11-23-09 | CSU Field House | Charleston Southern 99, Trinity College 50 | Box score |
| 11-21-09 | CSU Field House | Charleston Southern 80, Stetson 64 | Box score |
| 11/17/09 | McAlister Field House, Charleston, SC | Charleston Southern 61, The Citadel 60 | Box score |
| 11/13/09 | College Park, Md. | Maryland 89, Charleston Southern 51 | Box score |